Primary Lens Luxation
full health document
Eye Panel Examiners
Hearing Test Centres in the UK
Defects Advice - Collie Eye Anomoly (C.E.A.)
Collie Eye Anomaly (CEA) is an
inherited eye disease which manifests itself as a lesion on the back
the eye near the optic nerve.
lesion can be seen as a pale patch (Chorioretinal Hypoplasia - CH)
which is easily
visible to a vet carrying out an eye test on puppies less than seven
age, changes in the eye
hide the patch, making it harder to see, which is why there have been
instances of CEA failure puppies ‘going normal’ at
uncommon for affected dogs to
their sight except in the most severe cases, however the disease can be
by the offspring of an Affected or Carrier parent.
CEA, as the name suggests, is most
common in Collie breeds such as the Border, Rough and Smooth Collies,
as Shetland Sheepdogs, Australian Shepherds and Lancashire Heelers.
In Border Collies, the mode of
inheritance for CEA is known – it is passed on as a recessive
that in order to be
CEA, a dog needs two copies of the gene – one from each
both parents must be Carriers or
in order to pass on the condition. In
the past, to find out whether a dog was a Carrier or not, it was
carry out a test mating with a known Affected dog. If
this resulted in any Affected puppies – the
dog is a Carrier.
this test was
not foolproof, as there was only a 50% chance of getting Affected
puppies in a
test mating from a Carrier, and some dogs may have been thought to be
when they were not.
resulted in the production of CEA Affected puppies which might have to
culled or placed in pet homes at the risk of going blind - the morals
There are now two ways to screen for
CEA, and the BCCGB strongly recommends the use of both in order to
incidence of CEA in Border Collies. Firstly,
there is a DNA test available, so it
is possible to ascertain
whether your dog is Clear, a Carrier, or whether it is Affected. Secondly,
is the eye test – this is most
usefully carried out at between 5 and 7 weeks of age.
you are buying a Border Collie puppy,
ensure the breeder has had this done, (even if the parents are
It is not
recommended that anyone
breeds from an Affected dog, however Carriers can be bred from if they
to a known Clear dog.
some of the puppies being Carriers, so it would be wise to DNA test all
puppies so that the CEA status of each is known.
is worth emphasising that CEA is a congenital condition that can be
as soon as eye examination is possible and that it is diagnosed with
accuracy in young dogs. There is little doubt that, in those breeds
under the Eye Scheme, litter screening, combined with genetic testing,
best way of attempting to establish clear lines”
‘Hereditary eye disease in dogs’. Reprinted
January 2008 (updated January 2010).
testing can be done by a vet who
is a member of the BVA Eye Panel – a list of these vets is
available at the end
of this health section.
have eye drops to relax and dilate the pupil, and the vet will examine
of the eye.
takes a few
moments and causes the dog no discomfort. The
routine eye exam costs £48.00 per
dog, £41.00 for 2-24 dogs, and if
a group of over 25 dogs is assembled for testing, it costs just
eye exam will also
check for other eye problems such as PLL and CPRA (both explained in
detail below) and can pick up other abnormalities such as cataracts. Glaucoma,
however, must be screened for in a
£45.00 per litter of 5 or less puppies, or £9.00
in litters of 6 or
DNA testing for CEA status of dogs is
carried out by Optigen. The
website contains all the details of how to submit samples, including an
submission form, along with details of where clinics are being held -
one of these for the blood draw and bulk sample delivery will help to
A laboratory called IDEXX
in partnership with Optigen to do DNA testing for CEA –
the results do
take a little longer to come – up to 6 weeks and the results